Inside cells, DNA twists and coils itself into a variety of different secondary structures—including i-motifs (iMs) and ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

High-resolution imaging has revealed the internal layout of chromatin condensates, showing how DNA fibers fold and interact ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some ...

A new paper based on long-lost documents confirms that DNA discoverer Rosalind Franklin should be credited for discovering the double helix. When you purchase through links on our site, we may earn an ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...