A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

Tumors contain many different types of cells organized in complex spatial patterns that can influence how the disease progresses. Because of this, it is hard to predict how a tumor will develop and ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries ...

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body. It provides an ...

Applying single-cell RNA sequencing has led researchers to be able to profile the entire transcriptome of cells. However, these transcriptomes prove difficult to link back to their original location ...

The global initiative aims to profile up to 100,000 patient specimens to scale M-Optimus, the world model of biology, ...

Andreas Pfenning discusses the techniques being developed and used to study neuronal heterogeneity and the therapeutic potential of his work.

A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...